adrenal support
Supraglan
USD $50.95
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When we talk about immunity and overall wellness in our pets, we often think of vaccinations, nutrition, or regular exercise. But one often-overlooked part of the body that plays a vital role in maintaining your pet’s health and immunity is the adrenal glands. These small but powerful organs are crucial in regulating your pet’s response to stress, energy levels, and immune function.
In this blog, we will explore the fascinating world of adrenal glands and pet immunity and discuss how to support your pet’s adrenal health naturally.
What Are the Adrenal Glands?
Your pet has two adrenal glands, one located on top of each kidney. Though tiny in size, they are responsible for producing essential hormones that influence many of the body’s systems. These hormones include:
- Cortisol: the stress hormone that helps manage inflammation, blood sugar, and metabolism.
- Aldosterone: helps regulate electrolytes and fluid balance.
- Adrenaline (Epinephrine): released during fight-or-flight situations, boosting heart rate and energy.
These hormones are crucial for your pet’s ability to respond to stress, maintain immune balance, regulate metabolism, and stay energized.
How the Adrenal Glands Impact Your Pet’s Health
The adrenal glands don’t work in isolation, they’re part of a broader system known as the HPA axis (Hypothalamic-Pituitary-Adrenal axis), which controls your pet’s hormonal and stress responses.
Let’s look at three major areas impacted by adrenal function:
1. Metabolism and Energy
Cortisol, one of the main hormones produced by the adrenal cortex, plays a direct role in converting fats, proteins, and carbohydrates into usable energy. When adrenal function is disrupted, it can result in symptoms like fatigue, weight gain or loss, muscle weakness, or digestive issues.
2. Immune System Regulation
One of cortisol’s key roles is to keep the immune system in check. While a healthy amount of cortisol helps modulate inflammation and immune responses, too much or too little can suppress the immune system, making pets more vulnerable to infections, allergies, and chronic illnesses.
3. Response to Stress
Whether it’s environmental stress, separation anxiety, illness, or pain, the adrenal glands help your pet cope. Chronic stress can cause adrenal fatigue, which affects your pet’s resilience and recovery. In turn, this can disrupt sleep, digestion, and immune function.
Adrenal Dysfunction and Its Effects on Immunity
Adrenal disorders are not uncommon in dogs and cats, and they can significantly compromise the immune system. Two of the most recognized conditions are Cushing’s disease and Addison’s disease.
Cushing’s Disease (Hyperadrenocorticism)
Cushing’s disease occurs when the adrenal glands produce too much cortisol. Common signs include:
- Increased thirst and urination
- Potbellied appearance
- Hair loss
- Thinning skin
- Frequent infections
Excess cortisol suppresses immune responses, leaving pets more prone to bacterial, viral, or fungal infections. It also slows wound healing and increases inflammation throughout the body.
Addison’s Disease (Hypoadrenocorticism)
Addison’s disease, on the other hand, results from underactive adrenal glands, leading to a deficiency of cortisol and aldosterone. This can cause:
- Lethargy
- Vomiting or diarrhea
- Poor appetite
- Low heart rate
- Electrolyte imbalances (e.g., low sodium, high potassium)
Because cortisol helps regulate immune responses, a lack of it can cause immune dysfunction, poor stress tolerance, and frequent illness. In severe cases, an Addisonian crisis can be life-threatening without prompt veterinary care.
Supporting Adrenal Health Naturally
Whether your pet has a diagnosed adrenal condition or you simply want to keep their endocrine and immune systems strong, there are several natural ways to support adrenal gland health.
1. Reduce Stress
Chronic stress is a leading contributor to adrenal imbalance. Consider the following tips:
- Provide a calm, stable environment.
- Stick to routines, pets thrive on predictability.
- Use calming aids such as pheromone diffusers or anxiety wraps during stressful events.
- Consider gentle, natural calming supplements like Lesstress, which may help soothe nervous tension and support the HPA axis.
2. Optimize Nutrition
A nutrient-dense, species-appropriate diet is essential for adrenal support. Focus on:
- High-quality protein to support muscle maintenance and hormone production.
- Healthy fats, particularly omega-3s, for anti-inflammatory support.
For pets with adrenal disorders, feeding smaller, more frequent meals can help stabilize blood sugar levels and reduce the workload on the adrenal glands, which are involved in regulating metabolism and stress responses.
3. Use Natural Supplements for Support
At NHV, we’re passionate about using plant-based remedies to support wellness. For adrenal and immune health, here are a few standout products:
- Supraglan: Formulated to support the adrenal glands and endocrine system, it includes ingredients like eleuthero and astragalus to help balance cortisol levels naturally.
- Milk Thistle: Provides antioxidant and liver support, which is vital for hormone metabolism and detoxification.
- Multi Essentials: A daily multivitamin to fill nutritional gaps and balance immune function.
- Lesstress: The natural (non-addictive) sedative properties of Lesstress gently relax the nervous system and endocrine system.
Why Adrenal Health Matters
The adrenal glands and pet immune system are closely linked
The adrenal glands and pet immune system are closely linked. When the adrenal glands are functioning well, your pet is better able to handle stress, fight off infections, and maintain vitality. However, when they’re overworked or underperforming, it can lead to immune compromise, hormonal imbalances, and a host of health challenges.
If you suspect your pet may be experiencing adrenal dysfunction or if you want to explore natural ways to support their health, reach out to your veterinarian and explore NHV’s wide range of herbal support supplements designed to work alongside conventional care.
Adrenal Super Support and Nutritional Balance Kit
Supraglan, Milk Thistle & Multi Essentials
USD $141.85
bundle and save with pet expert kits
3 month supply for a small to medium size pet.
Help your pet combat Adrenal Disorders with all natural supplements formulated to ease symptoms, support your pet's recovery and improve their overall health.
Help your pet combat Adrenal Disorders with all natural supplements formulated to ease symptoms, support your pet's recovery and improve their overall health.
SUPRAGLAN
- Promotes the return of healthy skin and coat
- Produces hormones that help control appetite
- Helps body respond to stress and inflammation
- All natural, vet-formulated dietary supplement
- No additives or preservatives
MILK THISTLE
- Detoxifies the liver by removing toxins
- Improves liver function
- Supports regeneration of the liver
- Glycerin based and safe for long-term use
MULTI ESSENTIALS
- Stimulates metabolism
- Promotes healthy skin and coat
- Aids effective digestion
- Reduces fatigue and increases energy levels
- Helps fill nutritional voids
- item number
- BD5007
- weight
- 2.1
- volume
- 3 x 3.4 fl. oz. (100ml)
- form
- liquid
- life stages
- adult, senior, puppy/kitten
- made in
- Canada
Dosage Tab
To be taken twice daily. Determine your pet’s weight and then use the easy chart below to determine the correct dose. This is the minimum dosage.
Pet's Weight Dosage
0 - 15 lb = 0.5 ml
16 - 30 lb = 1.0 ml
31 - 45 lb = 1.5 ml
46 - 60 lb = 2.0 ml
61 - 75 lb = 2.5 ml
Over 75 lb = 3.0 ml
For small animals (rabbits, ferrets), avians and reptiles use 1 drop for every 2 lb of body weight.
How to Administer
Shake well before use. The easiest method is to use the dropper provided and place the drops into your pet’s food or favorite treat. You can also use the dropper and squirt directly into the pet’s mouth. Some pets can be finicky, if this occurs consider hiding the drops in foods most pet’s love such as fish, chicken or yogurt or a favorite treat. If your pet only eats dry food then soak a few kibbles at feeding time.
For Best Results
Herbal dietary supplements are beneficial to the health and well-being of your pet and are safe for long-term use. Every pet responds to natural herbal supplements differently, therefore it is important to be consistent and administer the product daily. Supplements generally take two to four weeks to take effect, however this will vary from one animal to the next.
Product Storage
All NHV Natural Pet Products are pure herbal extracts and contain no artificial additives, preservatives or coloring. Shelf life after opening is 6 months and must be refrigerated after opening.
Cautions and Contraindications
Do not use Supraglan in pregnant or nursing animals. Speak to your vet before using our products. A second visit is recommended if your pet’s condition does not improve, or deteriorates after continued use of the supplements.
All information provided by NHV Natural Pet Products is for educational purposes only.
Pet's Weight Dosage
To be taken twice daily. All NHV supplements are designed to be used together, and can, therefore, be given at once for convenience.
Select your pet's weight to determine the correct dose.
Tab Faq
What is the difference between adrenal disease, Addison's and Cushing's?
Addison's disease is also known as hypoadrenocorticism. This means that the adrenal system is underactive and does not produce enough natural corticosteroids for the body. Cushing's is also known as hyperadrenocoticism, so it is the opposite of Addison's, causing an overactive adrenal system which creates too much natural corticosteroid.
Where can I find additional help and resources?
Our pet experts are happy to help you with any questions you may have at any time. You can reach us via email, or on any of our social channels, or give us a call!
Can I put the supplements in food?
Yes, absolutely. In fact that is how most of our pet parents administer the supplements to their pets.
My pet has suspected adrenal disease. Can I still use this kit?
Yes, absolutely the kit will be helpful as proactive care as well.
-
Description
SUPRAGLAN
- Promotes the return of healthy skin and coat
- Produces hormones that help control appetite
- Helps body respond to stress and inflammation
- All natural, vet-formulated dietary supplement
- No additives or preservatives
MILK THISTLE
- Detoxifies the liver by removing toxins
- Improves liver function
- Supports regeneration of the liver
- Glycerin based and safe for long-term use
MULTI ESSENTIALS
- Stimulates metabolism
- Promotes healthy skin and coat
- Aids effective digestion
- Reduces fatigue and increases energy levels
- Helps fill nutritional voids
- item number
- BD5007
- weight
- 2.1
- volume
- 3 x 3.4 fl. oz. (100ml)
- form
- liquid
- life stages
- adult, senior, puppy/kitten
- made in
- Canada
-
Ingredients
Dosage Tab
To be taken twice daily. Determine your pet’s weight and then use the easy chart below to determine the correct dose. This is the minimum dosage.
Pet's Weight Dosage
0 - 15 lb = 0.5 ml
16 - 30 lb = 1.0 ml
31 - 45 lb = 1.5 ml
46 - 60 lb = 2.0 ml
61 - 75 lb = 2.5 ml
Over 75 lb = 3.0 ml
For small animals (rabbits, ferrets), avians and reptiles use 1 drop for every 2 lb of body weight.
How to Administer
Shake well before use. The easiest method is to use the dropper provided and place the drops into your pet’s food or favorite treat. You can also use the dropper and squirt directly into the pet’s mouth. Some pets can be finicky, if this occurs consider hiding the drops in foods most pet’s love such as fish, chicken or yogurt or a favorite treat. If your pet only eats dry food then soak a few kibbles at feeding time.For Best Results
Herbal dietary supplements are beneficial to the health and well-being of your pet and are safe for long-term use. Every pet responds to natural herbal supplements differently, therefore it is important to be consistent and administer the product daily. Supplements generally take two to four weeks to take effect, however this will vary from one animal to the next.Product Storage
All NHV Natural Pet Products are pure herbal extracts and contain no artificial additives, preservatives or coloring. Shelf life after opening is 6 months and must be refrigerated after opening.Cautions and Contraindications
Do not use Supraglan in pregnant or nursing animals. Speak to your vet before using our products. A second visit is recommended if your pet’s condition does not improve, or deteriorates after continued use of the supplements.All information provided by NHV Natural Pet Products is for educational purposes only.
-
Dosage
Pet's Weight Dosage
To be taken twice daily. All NHV supplements are designed to be used together, and can, therefore, be given at once for convenience.
Select your pet's weight to determine the correct dose.
Tab Faq
What is the difference between adrenal disease, Addison's and Cushing's?
Addison's disease is also known as hypoadrenocorticism. This means that the adrenal system is underactive and does not produce enough natural corticosteroids for the body. Cushing's is also known as hyperadrenocoticism, so it is the opposite of Addison's, causing an overactive adrenal system which creates too much natural corticosteroid.
Where can I find additional help and resources?
Our pet experts are happy to help you with any questions you may have at any time. You can reach us via email, or on any of our social channels, or give us a call!
Can I put the supplements in food?
Yes, absolutely. In fact that is how most of our pet parents administer the supplements to their pets.
My pet has suspected adrenal disease. Can I still use this kit?
Yes, absolutely the kit will be helpful as proactive care as well.
cushing's support
Cushing’s Disease Essentials Kit
USD $91.90
Cushing’s Disease Essentials Kit
Supraglan & Milk Thistle to Support Dog & Pet Cushing's Disease
USD $91.90
bundle and save with pet expert kits
3 month supply for a small to medium size pet.
This kit of NHV Supraglan and NHV Milk Thistle natural vet-formulated herbal supplements may help support healthy adrenal gland function, liver enzyme levels, help your pet to fight infections.
- Help balance the adrenal gland
- Helps balance the immune system and supports the body against infection
- Helps with symptoms of Cushing's like excessive thirst and urination, coat condition, and restlessness
This kit of NHV Supraglan and NHV Milk Thistle natural vet-formulated herbal supplements may help support healthy adrenal gland function, liver enzyme levels, help your pet to fight infections.
- Help balance the adrenal gland
- Helps balance the immune system and supports the body against infection
- Helps with symptoms of Cushing's like excessive thirst and urination, coat condition, and restlessness
If your cat or dog has Cushing’s disease, the NHV Cushing’s Disease Essentials Kit may be beneficial in supporting your pet's overall health and well-being. The combination of NHV Supraglan and NHV Milk Thistle are vet approved and formulated to work synergistically in supporting their pituitary and adrenal gland, liver, and kidney function.
This kit can be taken alone, or together with the conventional Cushing’s treatment for cats and dogs that your veterinarian prescribes. These all-natural supplements are safe to take long-term.
Symptoms of Cushing’s Disease
- Increased thirst and urination
- Increased appetite/overeating
- Weak muscles
- Heat intolerance & panting
- Thin skin & hair loss
- Bruising
- Potbelly or obesity
Dog and cat Cushing’s disease is caused by the overproduction of the hormone cortisol by the adrenal gland. Animals with this disease have a suppressed immune system caused by the excessive production of cortisol in the body and are likely to get bladder infections due to this.
SUPRAGLAN
- May reduce urination output
- May help to decrease thirst
- Promotes the return of healthy skin and coat
- Supports normal appetite and weight
- Helps balance the adrenal gland hormones
- Helps the body respond to stress and inflammation
MILK THISTLE
- Detoxifies the liver
- Improves liver function
- Helps support the regeneration of the liver
- Glycerin based and safe for long-term use
Support with NHV All-Natural Supplements
Supraglan is a natural herbal supplement that will help to balance the adrenal gland, improving the immune system and help the body fight infections. It may also aid in reducing thirst, excessive urination, appetite, help overall skin condition, and support the kidneys.
Milk Thistle helps support the liver and kidney function. Test results for animals that have Cushing’s indicated elevated liver enzyme levels and enlargement of the liver. Combing these products will help your pet live a healthy life. Visit our blog to read about other’s success in combating dog and pet Cushing’s disease with this essentials kit. Contact our pet experts if you have questions about options for Cushing’s treatment in cats & dogs.
- item number
- BD5028
- weight
- 1.4
- volume
- 2 x 3.4 fl. oz (100ml)
- form
- liquid
- life stages
- adult, senior, puppy/kitten
- made in
- Canada
SUPRAGLAN
Borage – Gently strengthens and improves adrenal function, and has been used for urinary issues and kidney inflammation.
Astragalus – Helps support the endocrine system, strengthens the immune system and acts as an anti-inflammatory. It has been found useful in helping the body recover from the effects of steroids, which affects the adrenal gland. Has both antibacterial and antiviral properties that aid your veterinarian’s recommended treatment for Cushing’s in cats & dogs.
Bistorte – A soothing anti-inflammatory that has a tonic effect on the liver and kidneys. In herbal medicine, it has been used to aid in urinary tract infections.
Eleuthero – A root that supports adrenal gland function, helps boost a sluggish metabolism, helps improve energy, and studies have shown that it improves the immune system.
Wild Yam – An herb that acts as a liver tonic, and helps normalize hormone production and kidney support. It helps with restlessness and nervousness.
Licorice – An herb that prevents the breakdown of the adrenal hormones. Improves digestion, helps boost immunity levels, and supports liver function.
Dandelion – A highly nutritious food that stimulates liver secretions, kidney function and improves digestion. High in natural vitamins and minerals.
MILK THISTLE
Milk Thistle – In herbal medicine, this herb has been used for centuries to support, regenerate and remove toxins from the liver. Milk Thistle contains silymarin - a compound that protects the liver and stimulates, the production of new cells. It has powerful antioxidant properties, which helps strengthen the liver's resistance to toxic compounds. A healthy liver can be key to the treatment of Cushing’s disease in dogs and pets.
In pets, Milk Thistle is beneficial for damaged kidneys, as it has been shown to decrease the amount of time to heal while helping eliminate toxins.
Pet's Weight Dosage
To be taken twice daily. All NHV supplements are designed to be used together, and can, therefore, be given at once for convenience.
Select your pet's weight to determine the correct dose.
To be taken twice daily. Determine your pet’s weight and then use the easy chart below to determine the correct dose. This is the minimum dosage.
Pet's Weight Dosage
0 - 15 lb = 0.5 ml
16 - 30 lb = 1.0 ml
31 - 45 lb = 1.5 ml
46 - 60 lb = 2.0 ml
61 - 75 lb = 2.5 ml
Over 75 lb = 3.0 ml
How to Administer
Refrigerate after opening.
Shake well. The easiest method is to use the dropper provided and place Supraglan and Milk Thistle drops into your dogs food or favorite treat. You can also use the dropper and squirt directly into the dogs mouth.
For Best Results
Herbal dietary supplements are beneficial to the health and well-being of your canine and are safe for long-term use. Every pet dog responds to natural herbal supplements differently, therefore it is important to be consistent and administer the product daily. Supplements generally take two to four weeks to take effect, however this will vary from one animal to the next.
Product Storage
All NHV Natural Pet Products are pure herbal extracts and contain no artificial additives, preservatives or coloring. Shelf life after opening is 6 months and must be refrigerated after opening.
Cautions and Contraindications
Do not use Supraglan in pregnant or nursing animals.
All information provided by NHV Natural Pet Products is for educational purposes only.
-
Description
If your cat or dog has Cushing’s disease, the NHV Cushing’s Disease Essentials Kit may be beneficial in supporting your pet's overall health and well-being. The combination of NHV Supraglan and NHV Milk Thistle are vet approved and formulated to work synergistically in supporting their pituitary and adrenal gland, liver, and kidney function.
This kit can be taken alone, or together with the conventional Cushing’s treatment for cats and dogs that your veterinarian prescribes. These all-natural supplements are safe to take long-term.
Symptoms of Cushing’s Disease
- Increased thirst and urination
- Increased appetite/overeating
- Weak muscles
- Heat intolerance & panting
- Thin skin & hair loss
- Bruising
- Potbelly or obesity
Dog and cat Cushing’s disease is caused by the overproduction of the hormone cortisol by the adrenal gland. Animals with this disease have a suppressed immune system caused by the excessive production of cortisol in the body and are likely to get bladder infections due to this.
SUPRAGLAN
- May reduce urination output
- May help to decrease thirst
- Promotes the return of healthy skin and coat
- Supports normal appetite and weight
- Helps balance the adrenal gland hormones
- Helps the body respond to stress and inflammation
MILK THISTLE
- Detoxifies the liver
- Improves liver function
- Helps support the regeneration of the liver
- Glycerin based and safe for long-term use
Support with NHV All-Natural Supplements
Supraglan is a natural herbal supplement that will help to balance the adrenal gland, improving the immune system and help the body fight infections. It may also aid in reducing thirst, excessive urination, appetite, help overall skin condition, and support the kidneys.
Milk Thistle helps support the liver and kidney function. Test results for animals that have Cushing’s indicated elevated liver enzyme levels and enlargement of the liver. Combing these products will help your pet live a healthy life. Visit our blog to read about other’s success in combating dog and pet Cushing’s disease with this essentials kit. Contact our pet experts if you have questions about options for Cushing’s treatment in cats & dogs.
- item number
- BD5028
- weight
- 1.4
- volume
- 2 x 3.4 fl. oz (100ml)
- form
- liquid
- life stages
- adult, senior, puppy/kitten
- made in
- Canada
-
Ingredients
SUPRAGLAN
Borage – Gently strengthens and improves adrenal function, and has been used for urinary issues and kidney inflammation.
Astragalus – Helps support the endocrine system, strengthens the immune system and acts as an anti-inflammatory. It has been found useful in helping the body recover from the effects of steroids, which affects the adrenal gland. Has both antibacterial and antiviral properties that aid your veterinarian’s recommended treatment for Cushing’s in cats & dogs.
Bistorte – A soothing anti-inflammatory that has a tonic effect on the liver and kidneys. In herbal medicine, it has been used to aid in urinary tract infections.
Eleuthero – A root that supports adrenal gland function, helps boost a sluggish metabolism, helps improve energy, and studies have shown that it improves the immune system.
Wild Yam – An herb that acts as a liver tonic, and helps normalize hormone production and kidney support. It helps with restlessness and nervousness.
Licorice – An herb that prevents the breakdown of the adrenal hormones. Improves digestion, helps boost immunity levels, and supports liver function.
Dandelion – A highly nutritious food that stimulates liver secretions, kidney function and improves digestion. High in natural vitamins and minerals.
MILK THISTLE
Milk Thistle – In herbal medicine, this herb has been used for centuries to support, regenerate and remove toxins from the liver. Milk Thistle contains silymarin - a compound that protects the liver and stimulates, the production of new cells. It has powerful antioxidant properties, which helps strengthen the liver's resistance to toxic compounds. A healthy liver can be key to the treatment of Cushing’s disease in dogs and pets.
In pets, Milk Thistle is beneficial for damaged kidneys, as it has been shown to decrease the amount of time to heal while helping eliminate toxins.
-
Dosage
Pet's Weight Dosage
To be taken twice daily. All NHV supplements are designed to be used together, and can, therefore, be given at once for convenience.
Select your pet's weight to determine the correct dose.
To be taken twice daily. Determine your pet’s weight and then use the easy chart below to determine the correct dose. This is the minimum dosage.
Pet's Weight Dosage
0 - 15 lb = 0.5 ml
16 - 30 lb = 1.0 ml
31 - 45 lb = 1.5 ml
46 - 60 lb = 2.0 ml
61 - 75 lb = 2.5 ml
Over 75 lb = 3.0 ml
How to Administer
Refrigerate after opening.
Shake well. The easiest method is to use the dropper provided and place Supraglan and Milk Thistle drops into your dogs food or favorite treat. You can also use the dropper and squirt directly into the dogs mouth.For Best Results
Herbal dietary supplements are beneficial to the health and well-being of your canine and are safe for long-term use. Every pet dog responds to natural herbal supplements differently, therefore it is important to be consistent and administer the product daily. Supplements generally take two to four weeks to take effect, however this will vary from one animal to the next.Product Storage
All NHV Natural Pet Products are pure herbal extracts and contain no artificial additives, preservatives or coloring. Shelf life after opening is 6 months and must be refrigerated after opening.Cautions and Contraindications
Do not use Supraglan in pregnant or nursing animals.All information provided by NHV Natural Pet Products is for educational purposes only.
adrenal support
Addison’s Disease Essential Support Kit
USD $91.90
Addison’s Disease Essential Support Kit
Milk Thistle & Supraglan to support dogs with Addison's disease.
USD $91.90
bundle and save with pet expert kits
3 month supply for a small to medium size pet.
Combat Addison's Disease with all natural supplements formulated to ease symptoms and restore strength and vitality to your pet.
Combat Addison's Disease with all natural supplements formulated to ease symptoms and restore strength and vitality to your pet.
Addison’s Disease, or hypoadrenocorticism, occurs when the adrenal glands do not produce enough hormones. The adrenal glands are located just in front of the kidneys and have two parts – the cortex and the medulla.
The adrenal cortex produces mineralocorticoids (of which the most potent naturally occurring is aldosterone), which help to control the balance of sodium and potassium salts. Glucocorticoids, which are involved in metabolizing nutrients as well as in reducing inflammation and, also produces sex hormones such as estrogen and progesterone.
The adrenal medulla plays an important role in response to stress or low blood sugar (glucose). It releases epinephrine (adrenaline) and norepinephrine, which increase heart output, blood pressure, and blood glucose, and slow digestion.
Addison's Disease is a deficiency in secretion of hormones by the adrenal gland and usually mineralocorticoid and glucocorticoid hormones are both decreased.
Addison’s disease is more common in young to middle aged dogs and occasionally in horses. The disease may be familial in Standard Poodles, West Highland White Terriers, Great Danes, Bearded Collies, Portuguese Water Dogs and a variety of other breeds. The cause of the primary adrenocortical failure usually is unknown, although most cases probably result from an autoimmune process. Other causes include destruction of the adrenal gland by granulomatous disease, metastatic tumor, hemorrhage or infarction. It can also be caused by the medications used to treat overactive adrenal glands, or Cushing’s disease.
Clinical signs include intermittent vomiting, diarrhea, decreased appetite, weight loss, and sometimes dark, bloody diarrhea. Lethargy, depression, and weakness are also common. Sometimes hair loss and increased thirst and urination occurs.
The diagnosis requires laboratory testing, because no clinical signs are specific for Addison’s disease.
Pets in an acute Addisonian crisis require hospitalization and intensive care. For most dogs with hypoadrenocorticism, lifelong supplementation with mineralocorticoids is needed.
SUPRAGLAN
- Regulates water and electrolyte levels (reducing urine output & thirst)
- Promotes the return of healthy skin and coat
- Produces hormones that help control appetite
- Helps body respond to stress and inflammation
- All-natural, vet-formulated dietary supplement
- No additives or preservatives
MILK THISTLE
- Detoxifies the liver by removing toxins
- Improves liver function
- Supports regeneration of the liver
- Glycerin based and safe for long-term use
- item number
- BD5006
- weight
- 1.4
- volume
- 2 x 3.4 fl. oz. (100ml)
- form
- liquid
- life stages
- adult, senior, puppy/kitten
- made in
- Canada
SUPRAGLAN
Borage (Borago officinalis) - Borage has antibacterial, antihyperlipidemic, anti-inflammatory, antiplatelet effects and it is an herb that is know for its ability to support adrenal function. Borage contains gamma-linolenic acid (GLA), an omega-6 polyunsaturated fatty acid, that has effects on components of the renin-angiotensin-aldosterone axis, balancing the secretion of aldosterone that is reduced in Addison`s disease.
Astragalus (Astragalus membranaceus) - Astragalus has properties that help to balance the immune system which can be compromised in pets with Addison`s disease. Bistort (Polygonum bistorta) Bistort is an astringent, soothing, anti-inflammatory herb that has tonic effect on the liver and kidneys. It also helps with gastrointestinal issues, like diarrhea which is one of the symptoms present in Addison`s disease.
Eleuthero (Eleutherococcus senticosus) - Eleuthero is a tonic with a modulating effect on major stress axis including pituitary glands, hypothalamus, and adrenal glands. It can increase resistance to infection that help to support the adrenal gland. In addition, it protects the immune system, and contains powerful antioxidants that help scavenge free radicals.
Wild Yam (Diocorea villosa) - Wild Yam is anti-inflammatory herb that contains steroidal saponins (dioscin, dogenin), which is used in the preparation of steroid hormones and helps normalize hormone production which is decreased in Addison` disease.
Licorice (Glycyrrhiza glabra) - Licorice is beneficial for the adrenal gland, endocrine, digestive and respiratory system. The main phytochemical of licorice is glycyrrhizic acid helps stimulate the adrenal gland. Licorice also has an anti-inflammatory action like hydrocortisone and another corticosteroid hormones.
Dandelion - Dandelion has anti-inflammatory, antineoplastic, antioxidant, endocrine, gastrointestinal, hepatic and hypoglycemic effects. Dandelion is an anti-inflammatory and tonic herb that helps protect the kidneys which can be injured when the pet presents with Addison`s disease. It can also stimulate liver secretion and improve digestion.
MILK THISTLE
Silybum marianum - As renal failure frequently occurs in Addison’s disease, Milk Thistle can be very beneficial because of its renal protective effects. Several animal studies support the renal protective effects of silymarin against toxic agents. The liver protective properties of Milk Thistle can also be beneficial for pets who take pharmaceutical medications for the treatment of Addison’s disease.
Pet's Weight Dosage
To be taken twice daily. All NHV supplements are designed to be used together, and can, therefore, be given at once for convenience.
Select your pet's weight to determine the correct dose.
To be taken twice daily. Determine your pet’s weight and then use the easy chart below to determine the correct dose. This is the minimum dosage.
Pet's Weight Dosage
0 - 15 lb = 0.5 ml
16 - 30 lb = 1.0 ml
31 - 45 lb = 1.5 ml
46 - 60 lb = 2.0 ml
61 - 75 lb = 2.5 ml
Over 75 lb = 3.0 ml
For small animals (rabbits, ferrets), avians and reptiles use 1 drop for every 2 lb of body weight.
How to Administer
Shake well before use. The easiest method is to use the dropper provided and place the drops into your pet’s food or favorite treat. You can also use the dropper and squirt directly into the pet’s mouth. Some pets can be finicky, if this occurs consider hiding the drops in foods most pet’s love such as fish, chicken or yogurt or a favorite treat. If your pet only eats dry food then soak a few kibbles at feeding time.
For Best Results
Herbal dietary supplements are beneficial to the health and well-being of your pet and are safe for long-term use. Every pet responds to natural herbal supplements differently, therefore it is important to be consistent and administer the product daily. Supplements generally take two to four weeks to take effect, however this will vary from one animal to the next.
Product Storage
All NHV Natural Pet Products are pure herbal extracts and contain no artificial additives, preservatives or coloring. Shelf life after opening is 6 months and must be refrigerated after opening.
Cautions and Contraindications
Do not use Supraglan in pregnant or nursing animals. Speak to your vet before using our products. A second visit is recommended if your pet’s condition does not improve, or deteriorates after continued use of the supplements.
All information provided by NHV Natural Pet Products is for educational purposes only.
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Description
Addison’s Disease, or hypoadrenocorticism, occurs when the adrenal glands do not produce enough hormones. The adrenal glands are located just in front of the kidneys and have two parts – the cortex and the medulla.
The adrenal cortex produces mineralocorticoids (of which the most potent naturally occurring is aldosterone), which help to control the balance of sodium and potassium salts. Glucocorticoids, which are involved in metabolizing nutrients as well as in reducing inflammation and, also produces sex hormones such as estrogen and progesterone.
The adrenal medulla plays an important role in response to stress or low blood sugar (glucose). It releases epinephrine (adrenaline) and norepinephrine, which increase heart output, blood pressure, and blood glucose, and slow digestion.
Addison's Disease is a deficiency in secretion of hormones by the adrenal gland and usually mineralocorticoid and glucocorticoid hormones are both decreased.
Addison’s disease is more common in young to middle aged dogs and occasionally in horses. The disease may be familial in Standard Poodles, West Highland White Terriers, Great Danes, Bearded Collies, Portuguese Water Dogs and a variety of other breeds. The cause of the primary adrenocortical failure usually is unknown, although most cases probably result from an autoimmune process. Other causes include destruction of the adrenal gland by granulomatous disease, metastatic tumor, hemorrhage or infarction. It can also be caused by the medications used to treat overactive adrenal glands, or Cushing’s disease.
Clinical signs include intermittent vomiting, diarrhea, decreased appetite, weight loss, and sometimes dark, bloody diarrhea. Lethargy, depression, and weakness are also common. Sometimes hair loss and increased thirst and urination occurs.
The diagnosis requires laboratory testing, because no clinical signs are specific for Addison’s disease.
Pets in an acute Addisonian crisis require hospitalization and intensive care. For most dogs with hypoadrenocorticism, lifelong supplementation with mineralocorticoids is needed.
SUPRAGLAN
- Regulates water and electrolyte levels (reducing urine output & thirst)
- Promotes the return of healthy skin and coat
- Produces hormones that help control appetite
- Helps body respond to stress and inflammation
- All-natural, vet-formulated dietary supplement
- No additives or preservatives
MILK THISTLE
- Detoxifies the liver by removing toxins
- Improves liver function
- Supports regeneration of the liver
- Glycerin based and safe for long-term use
- item number
- BD5006
- weight
- 1.4
- volume
- 2 x 3.4 fl. oz. (100ml)
- form
- liquid
- life stages
- adult, senior, puppy/kitten
- made in
- Canada
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Ingredients
SUPRAGLAN
Borage (Borago officinalis) - Borage has antibacterial, antihyperlipidemic, anti-inflammatory, antiplatelet effects and it is an herb that is know for its ability to support adrenal function. Borage contains gamma-linolenic acid (GLA), an omega-6 polyunsaturated fatty acid, that has effects on components of the renin-angiotensin-aldosterone axis, balancing the secretion of aldosterone that is reduced in Addison`s disease.
Astragalus (Astragalus membranaceus) - Astragalus has properties that help to balance the immune system which can be compromised in pets with Addison`s disease. Bistort (Polygonum bistorta) Bistort is an astringent, soothing, anti-inflammatory herb that has tonic effect on the liver and kidneys. It also helps with gastrointestinal issues, like diarrhea which is one of the symptoms present in Addison`s disease.
Eleuthero (Eleutherococcus senticosus) - Eleuthero is a tonic with a modulating effect on major stress axis including pituitary glands, hypothalamus, and adrenal glands. It can increase resistance to infection that help to support the adrenal gland. In addition, it protects the immune system, and contains powerful antioxidants that help scavenge free radicals.
Wild Yam (Diocorea villosa) - Wild Yam is anti-inflammatory herb that contains steroidal saponins (dioscin, dogenin), which is used in the preparation of steroid hormones and helps normalize hormone production which is decreased in Addison` disease.
Licorice (Glycyrrhiza glabra) - Licorice is beneficial for the adrenal gland, endocrine, digestive and respiratory system. The main phytochemical of licorice is glycyrrhizic acid helps stimulate the adrenal gland. Licorice also has an anti-inflammatory action like hydrocortisone and another corticosteroid hormones.
Dandelion - Dandelion has anti-inflammatory, antineoplastic, antioxidant, endocrine, gastrointestinal, hepatic and hypoglycemic effects. Dandelion is an anti-inflammatory and tonic herb that helps protect the kidneys which can be injured when the pet presents with Addison`s disease. It can also stimulate liver secretion and improve digestion.
MILK THISTLE
Silybum marianum - As renal failure frequently occurs in Addison’s disease, Milk Thistle can be very beneficial because of its renal protective effects. Several animal studies support the renal protective effects of silymarin against toxic agents. The liver protective properties of Milk Thistle can also be beneficial for pets who take pharmaceutical medications for the treatment of Addison’s disease.
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Dosage
Pet's Weight Dosage
To be taken twice daily. All NHV supplements are designed to be used together, and can, therefore, be given at once for convenience.
Select your pet's weight to determine the correct dose.
To be taken twice daily. Determine your pet’s weight and then use the easy chart below to determine the correct dose. This is the minimum dosage.
Pet's Weight Dosage
0 - 15 lb = 0.5 ml
16 - 30 lb = 1.0 ml
31 - 45 lb = 1.5 ml
46 - 60 lb = 2.0 ml
61 - 75 lb = 2.5 ml
Over 75 lb = 3.0 ml
For small animals (rabbits, ferrets), avians and reptiles use 1 drop for every 2 lb of body weight.
How to Administer
Shake well before use. The easiest method is to use the dropper provided and place the drops into your pet’s food or favorite treat. You can also use the dropper and squirt directly into the pet’s mouth. Some pets can be finicky, if this occurs consider hiding the drops in foods most pet’s love such as fish, chicken or yogurt or a favorite treat. If your pet only eats dry food then soak a few kibbles at feeding time.For Best Results
Herbal dietary supplements are beneficial to the health and well-being of your pet and are safe for long-term use. Every pet responds to natural herbal supplements differently, therefore it is important to be consistent and administer the product daily. Supplements generally take two to four weeks to take effect, however this will vary from one animal to the next.Product Storage
All NHV Natural Pet Products are pure herbal extracts and contain no artificial additives, preservatives or coloring. Shelf life after opening is 6 months and must be refrigerated after opening.Cautions and Contraindications
Do not use Supraglan in pregnant or nursing animals. Speak to your vet before using our products. A second visit is recommended if your pet’s condition does not improve, or deteriorates after continued use of the supplements.All information provided by NHV Natural Pet Products is for educational purposes only.
Dr. Mehdi Esmatparast, DVM, Ph.D.
Published: April 18, 2025
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Description
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Ingredients
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Dosage