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Resp-Aid™ for Cats

For Coughs, Respiratory Disorders, and Bronchial Infections in Cats

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Study on Resp-Aid Effect on Cat & Dog Asthma

Clinical Trials & Research 3 min read
pug looking sad because of dog asthma

We are excited to announce our collaborative clinical research with the University of Saskatchewan and the University of Calgary, focusing on NHV Resp-Aid and its effect on cat and dog asthma. Our in-house vet, Dr. Amanda Nascimento, led the research.

What is Cat & Dog Asthma?

Before all else, let’s first define this condition. Asthma is a serious form of respiratory disease-causing high mortality in the world. Resp-Aid, on the other hand, is an innovative proprietary formula developed by NHV Natural Pet Products to support respiratory disorders and bronchial infections.

The lungs from asthmatic animals treated with Resp-Aid showed considerably less inflammation and histopathology.

The blend is composed of 9 herbs: Coltsfoot (Tussilago farfar), Marshmallow (Althaea officilanes), Plantain (Pantago major), Mullein (Verbascum Thapsus), Horehound (Marrubium vulgare) and Licorice (Gycyrrhiza glabra), Lobelia (Lobelia inflata), Ginger (Zingiber officinale), Myrrh (Commiphora momol). These herbs have traditional been for respiratory treatments such as asthma to reduce coughing and phlegm/mucous production. They are also known to have anti-inflammatory and immunomodulatory activities. However, the effects of these herbs in this formula for asthma have not been scientifically studied.

Research Objective, Material and Method

Based on the theoretical benefits of Resp-Aid, we conducted a series of studies to explore the efficacy, safety and mechanism of action of Resp-Aid. We hypothesized the treatment with Resp-Aid can alter pulmonary immune responses.

graph for cat and dog asthma study  with NHV Resp-Aid

Therefore, to study this, we treated asthmatic and non-asthmatic animals with Resp-Aid.

graph for cat and dog asthma study  with NHV Resp-Aid

They received 1 drop of Resp-Aid twice daily for 7 days. On day 7 of the treatment with Resp-Aid whole body plethysmography chambers* (WBP) were utilized measuring airway hyperresponsiveness** (AHR). Also, they are monitored for respiratory airflow. For understanding inflammatory differences between the groups, after the treatment with Resp-Aid bronchoalveolar lavage (BAL) and lungs where examined.

*an instrument that measures the changes in volume within the organ

**a characteristic feature of asthma and consists of an increased sensitivity of the airways

Here Is What The Researchers Found:

result for cat and dog asthma study  with NHV Resp-Aid

Asthmatic animals that received Resp-Aid had lower AHR (They could breath better) compared to asthmatic animals that did not receive Resp-Aid (P<0.05).

Asthmatic animals that received Resp-Aid had lower total leukocytes (inflammatory cells) compared to asthmatic animals that did not receive Resp-Aid (P<0.05).

The lungs from asthmatic animals treated with Resp-Aid showed considerably less inflammation and histopathology compared with asthmatic animals’ lungs that did not receive Resp-Aid.

All in all, this data shows that Resp-Aid alleviates asthma. It may be a potential target for therapeutic intervention in allergic lung disease or asthma or other pulmonary infections.


If you have any questions about cat and dog asthma or anything else, contact our team of pet experts! We are happy to help.

NHV Pet Experts

NHV Pet Experts

We have a dedicated group of pet expert professionals, including veterinarians, vet techs, and other pet professionals to guide you through any questions. We’re committed to your pet’s wellness and can offer additional tips, resources, nutritional advice, and more.

Published: July 12, 2019

2 replies

  1. Joanne says:

    This seems misleading. This article is titled “Study on Resp-Aid Effect on Cat & Dog Asthma” but the linked study was on mice, not cats or dogs. One of the author vets works for NHV. Lobelia is toxic to cats.

    1. Team NHV says:

      Thank you for raising this — it’s an important question, and we appreciate the chance to clarify.

      You are correct that the mechanistic portion of the research (the part investigating airway inflammation, cytokine activity, and lung tissue response) was conducted using a mouse asthma model. This is standard practice in both veterinary and human medicine, because rodent models allow researchers to study biological pathways with a level of precision that isn’t feasible in companion animals.

      However, that laboratory model is only one part of the overall research.

      Resp-Aid has also been evaluated directly in cats and dogs through real-world veterinary case follow-ups, observational studies, and field use. These assessments focus on safety, dosing, palatability, and clinical response in the species actually using the product. This companion-animal data is separate from the mechanistic work and provides essential insight into how the formula performs in practice.

      We recognize that our current blog article emphasizes the mechanistic study and does not yet include the real-world clinical observations in pets. We’re updating the article now to clearly distinguish these two layers of research so readers have a complete and accurate picture of the evidence pathway:

      -Foundational mechanistic study in a mouse asthma model

      -Clinical and observational evaluation in real dogs and cats using Resp-Aid

      -Both components contribute complementary information:

      -The mechanistic work helps explain how and why the formula behaves the way it does.

      -The companion-animal observations show what actually happens when dogs and cats use it under veterinary guidance.

      Regarding the concern about an NHV veterinarian being an author: this affiliation is openly disclosed and is common in both supplement and pharmaceutical research. Formulation experts participate to ensure accuracy in how the product is used and interpreted. Importantly, peer review provides independent scientific oversight, helping to minimize bias regardless of author affiliation.

      As for lobelia, you are right that raw lobelia plants can be toxic at high or uncontrolled doses. In Resp-Aid, the lobelia root extract is used in a very low, carefully controlled amount that falls within safety parameters for dogs and cats when used as directed. As with many therapeutic ingredients — herbal or pharmaceutical — dose, part used, and extration method are strong determination factors of toxicity. Our veterinary team formulates with wide safety margins, and we always recommend veterinary guidance for pets with complex respiratory conditions.

      We truly appreciate your diligence. Questions like yours help us continuously improve how we communicate research so that it remains clear, transparent, and scientifically accurate — especially as we update the article to include both the mechanistic findings and the companion-animal data.

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